Never have had the pleasure in either self-play, real life, or med-play. Closest thing was NO2 at the dentist. Anesthesia is my favorite medical kink hands down. Close second is surgical gloves, combine those two and it's game over. Luckily there are sites that cater with videos, masks, tubes, abmu bags(I know not anesthesia but still good, esecpically for dom/sub kinda thing) ect.