My former wife was big on Glycerin Suppositories, her mother started her on them when little.
She also asked me for enemas, must have given her over 200 with various equipment.
When we went to the Ocean on vacation, the first night after dinner would go to a drugstore on boardwalk and buy a jar.
At various times had jars of 12, 25, 50 and a 100.
Often said: "Don't tie up the bathroom, I have one up there".
Once I bought her infant ones, she had to take several.
At least two times, when asleep gave her an enema up her big, shapely fanny. Maybe a suppository, too.
She would wake up and say: "that's mean". And run to the bathroom.